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Aspirin cuts death risk after breast cancer

Large study of nurses showed 50 percent lower risk cancer would spread

WASHINGTON - Breast cancer survivors who take aspirin regularly may be less likely to die or have their cancer return, U.S. researchers reported Tuesday.

The study of more than 4,000 nurses showed that those who took aspirin — usually to prevent heart disease — had a 50 percent lower risk of dying from breast cancer and a 50 percent lower risk that the cancer would spread.

"This is the first study to find that aspirin can significantly reduce the risk of cancer spread and death for women who have been treated for early stage breast cancer, " said Dr. Michelle Holmes of Harvard Medical School, who led the study published in the Journal of Clinical Oncology.

"If these findings are confirmed in other clinical trials, taking aspirin may become another simple, low-cost and relatively safe tool to help women with breast cancer live longer, healthier lives," Holmes added in a statement.

Holmes and her team studied 4,164 female registered nurses taking part in the Nurses' Health Study, an ongoing analysis of a wide range of health issues.

They started in 1976, looking at who took aspirin, watching for breast cancer and all causes of death until 2006.

Over this time, 341 of the nurses died of breast cancer.

Women who took aspirin two to five days a week had a 60 percent reduced risk of their cancer spreading and a 71 percent lower risk of breast cancer death. Six to seven aspirins a week lowered the risk of spread by 43 percent and the risk of breast cancer death by 64 percent.

Most of the women were taking low-dose aspirin to prevent heart attacks and stroke.

Ibuprofen and naproxen appear to lower risk too
Other drugs in the same class as aspirin also apparently lowered the risks, too. These drugs, called non-steroidal inflammatory drugs or NSAIDs, include ibuprofen and naproxen but not acetaminophen, also known as paracetamol.

But there was not enough data on these drugs to give a clear answer.

The researchers said they are not sure how aspirin and other NSAIDS may affect tumors but it could be by lowering inflammation. Other studies have shown that aspirin and ibuprofen can lower colon cancer risk, for instance.

"Aspirin has relatively benign adverse effects compared with cancer chemotherapeutic drugs and may also prevent colon cancer, cardiovascular disease, and stroke," the researchers wrote. It affected both estrogen-positive tumors and those not fueled by the hormone.

Holmes' team stressed that patients should not take aspirin while undergoing radiation or chemotherapy because of the risk of side effects.

And aspirin can cause stomach bleeding so it should not be taken without a doctor's supervision.

Copyright 2010 Reuters.

 

 

 

 

This press release, and any related research and/or opinions, are those of the authors and do not necessarily reflect the research and/or opinions of RadNet Management, Inc or Grove Diagnostic Imaging

 


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MRI, MRA, CT, Ultrasound, Vascular Ultrasound, PET/CT, Nuclear Med, Nuclear Cardio, X-Ray, Open MRI, Fluoro, Arthrograms, Mammography, Breast Ultrasound, DEXA, Stereotactic Breast Biopsy, Breast Cancer Reconstructive Surgery, Helical CT, MR Angiography, High Field MRI, Orange County, Mission Viejo, Los Angeles, Anaheim, Santa Ana, Irvine, community, Southern California, California, orthopedic, sports medicine, bone fracture, Bone Density, Bone Densitometer, Osteoporosis, GE Lunar, broken bones, hip, knee, carpel tunnel, spine, back, Radiology, Diagnostics Imaging, Digital Breast MRI, Breast Biopsy, iCAD, DynaCAD, MRI CAD, Mammo CAD, Women's, Women's Imaging, Breast Cancer Screening
Here is partial list of some of the areas we service:
Los Angeles County:
Agoura Hills, Alhambra, Arcadia, Artesia, Azusa, Baldwin Park, Bellflower, Beverly Hills, Big Pines, Burbank, Carson, Century City, Cerritos, Chatsworth, China Town, City of Industry, Claremont, Commerce, Compton, Covina, Culver City, Downtown LA, Downey, Eagle Rock, El Monte, El Segundo, Encino, Gardena, Glendale, Glendora, Granada Hills, Hawaiian Gardens, Hawthorne, Hermosa Beach, Hidden Hills, Highland Park, Hollywood, Inglewood, Irwindale, Japan Town, Korea Town, La Canada/Flintridge, La Crescenta, La Habra, La Mirada, La Puente, La Verne, Lakewood, Lancaster, Lenox, Lomita, Long Beach, Los Angeles, Los Nietos, Lynwood, Manhattan Beach, Marina Del Rey, Monterey Park, Montrose, Northridge, Norwalk, Palmdale, Palos Verdes Estates, Paramount, Pasadena, Pico Rivera, Pomona, Rancho Palos Verdes, Redondo Beach, Reseda, Rolling Hills Estates, San Fernando Valley, San Gabriel, San Marino, Santa Clarita, Santa Fe Springs, Santa Monica, Signal Hill, South Pasadena, Temple City, Torrance, Valinda, Van Nuys, Ventura County, Verdugo City, Walnut, West Covina, West Hollywood, Westlake Village, Westwood, Whittier and all other cities and communities of Los Angeles County.

Orange County:
Aliso Viejo, Anaheim, Balboa Island, Brea, Buena Park, Capistrano Beach, Corona Del Mar, Costa Mesa, Coto de Caza, Cowan Heights, Cypress, Dana Point, El Modena, El Toro, Foothill Ranch, Fountain Valley, Fullerton, Garden Grove, Huntington Beach, Irvine, La Habra, Laguna Beach, Laguna Hills, Laguna Niguel, Lake Forest, Leisure World, Lemon Heights, Los Alamitos, Mission Viejo, Modjeska Canyon, Newport Beach, Orange, Orange Park Acres, Placentia, Rancho San Margarita, Rossmoor, San Clemente, Santa Ana, Seal Beach, Silverado Canyon, Stanton, Sunset Beach, Surfside, Tustin, Villa Park, Westminster, Yorba Linda and all other cities and communities of Orange County.

San Bernardino County:
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Riverside County:
Anza, Arlington, Banning, Beaumont, Blythe, Cabazon, Calimesa, Canyon Lake, Cathedral City, Cherry Valley, Coachella, Corona, Desert Hot Springs, Edgemont, El Cerrito, Gilman, Glen Avon, Glenn Valley, Hemet, High Grove, Home Gardens, Homeland, Hot Springs, Idyllwild, Indian Wells, Indio, La Sierra, Lake Elsinore, Lakeview, La Quinta, Mecca, Mead Valley, Meadow Brook, Mira Loma, Moreno Valley, Murrieta, Murrieta Hot Springs, Norco, Nuevo, Palm Desert, Palm Springs, Perris, Quail Valley, Riverside, Rancho Mirage, Ripley, Rubidoux, Sage, San Jacinto, Sun City, Temecula, Temescal Canyon, Thousand Palms, Valle Vista, White Water, Winchester and all other cities and communities of Riverside County.

Imperial County:
Brawley, Calexico, Calipatria, El Centro, Holtville, Imperial, Westmorland and all other cities and communities of Imperial County.

Ventura County:
Camarillo, Fillmore, Moorpark, Ojai, Oxnard, Port Hueneme, San Buenaventura, Santa Paula, Simi Valley, Thousand Oaks and all other cities and communities of Ventura County. 

As well as the following zip-codes: 91302 Calabasas, Hidden Hills, 91304 west hills, 91307 west hills, 91303 Woodland Hills, 91311 Chatsworth, 91312 Chatsworth, 91313 Chatsworth, 91316 Encino, 91324 Northridge, 91325 Northridge, 91326 Northridge, 91327 Northridge, 91328 Northridge, 91329 Northridge, 91330 Northridge, 91356 Tarzana, 91357 Tarzana, 91364 Woodland Hills, 91365 Woodland Hills, 91367 Woodland Hills, 91371 Woodland Hills, 91372 Woodland hills, 91399 Calabasas, 91401 Sherman Oaks, 91411 Sherman Oaks, 91413 Sherman Oaks, 91423 Sherman Oaks, 91495 Sherman Oaks, Plumbing, Burbank (91501,91502,91503, 91504, 91505, 91506, 91507, 91508, 91510, 91521, 91522, 91523, 91526) North Hills 91393, Granada Hills 91394, Mission Hills 91395, Canoga Park 91396, Van Nuys (91404, 91405, 91406, 91407, 91408, 91409, 91410, 91426, 91436, 91470, 91482,91496, 91497,91499) Reseda 91335, 91337, 91343 North Hills, 91344 Granada Hills, 91346 mission hills, Studio City 91607, Universal City 91608, Studio City 91614, Universal City 91618, North Hollywood (91601, 91602, 91603, 91604, 91605, 91606, 91609, 91610, 91611, 91612, 91615, 91616, 91617, Santa Clarita, 91310, 91321, 91322, 91350, 91351, 91354, 91355, 91380, 91381, 91382, 91383, 91384, 91385, 91386, 91387, 91390, Valencia, 91354, 91355, 91380, 91385, Saugus, 91350, 91390, Newhall, 91321, 91322, 91381, 91382, Stevenson Ranch, 91381, Stevensons Ranch, Stevenson's Ranch, Thousand Oaks, 91319, 91320, 91358, 91359, 91360, 91361, 91362, 91363, Agoura Hills, 91301, 91376, 91377, Westlake Village, 91359, 91361, 91362, 91363, Oak Park, 91301, 91377, Simi Valley, CA:93062, 93063, 93064, 93065, 93093, 93094, 93099, Moorpark, CA:93020, 93021